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🦀 ClawHub

Genome Report

by @nomadrex

Analyze 23andMe raw genome data to generate comprehensive health, trait, and family comparison reports. Supports cardiovascular, cognitive, metabolic, pharma...

Versionv1.0.0

Downloads323

#legal #health

View on ClawHub →

TERMINAL

clawhub install genome-report

📖 About This Skill

name: genome-report description: Analyze 23andMe raw genome data to generate comprehensive health, trait, and family comparison reports. Supports cardiovascular, cognitive, metabolic, pharmacogenomic, athletic, and ancestry analysis. Use when user asks to analyze genome data, 23andMe files, genetic reports, SNP analysis, health risk from DNA, or family genetic comparison.

Genome Report

Analyze 23andMe v5 raw data files and generate health/trait reports with risk scoring.

Usage

python3 skills/genome-report/scripts/genome_report.py  [options]

Options

| Flag | Values | Default | Description | |------|--------|---------|-------------| | --category | all\|cardio\|cognitive\|metabolic\|pharma\|athletic\|traits | all | Category filter | | --output | text\|json\|html | text | Output format | | --output-path | filepath | auto | HTML output path | | --family DIR | directory path | — | Family comparison mode |

Examples

# Full report to console
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt
HTML report for one category
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt --category cardio --output html
Family comparison
python3 skills/genome-report/scripts/genome_report.py --family ~/genomes/ --output html

Input Format

23andMe v5 raw data (tab-separated): rsid chromosome position genotype

Lines starting with # are skipped. Genotypes marked -- (no-call) are excluded.

Output

Text: Console output with risk bars and color-coded SNP details

JSON: Structured data with scores and per-SNP results

HTML: Styled report with risk score cards and color-coded tables

Categories & Coverage

~55 curated SNPs across 6 categories:

Cardiovascular — blood pressure, cholesterol, cardiac rhythm, CAD risk

Cognitive — memory, dopamine, BDNF, social cognition, brain volume

Metabolic — diabetes risk, MTHFR, lactose, alcohol, iron metabolism

Pharmacogenomics — warfarin, clopidogrel, CYP2D6, CYP2C19 drug metabolism

Athletic — muscle fiber type, endurance, recovery, injury risk

Traits — eye color, hair color, earwax, bitter taste, asparagus smell

SNP Database

The SNP reference data lives in references/snp_database.json. Edit this file to add/update SNPs without changing the script. Each entry has: rsid, gene, category, trait, risk_allele, and genotype-specific effect descriptions.

Constraints

Pure Python 3.9+ — no external dependencies

Not medical advice — educational/informational only

💡 Examples

# Full report to console
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt
HTML report for one category
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt --category cardio --output html
Family comparison
python3 skills/genome-report/scripts/genome_report.py --family ~/genomes/ --output html

⚙️ Configuration

Examples

# Full report to console
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt
HTML report for one category
python3 skills/genome-report/scripts/genome_report.py ~/my_genome.txt --category cardio --output html
Family comparison
python3 skills/genome-report/scripts/genome_report.py --family ~/genomes/ --output html

🔒 Constraints

Pure Python 3.9+ — no external dependencies

Not medical advice — educational/informational only