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Single-cell Pipeline

by @aipoch-ai

Generate single-cell RNA-seq analysis code templates for Seurat and Scanpy, supporting QC, clustering, visualization, and downstream analysis. Trigger when u...

Versionv1.0.0
⚑ When to Use
TriggerAction
- Need standardized QC and preprocessing workflows
- Performing batch correction across multiple samples/datasets
- Running dimensionality reduction and clustering
- Identifying cell type-specific marker genes
- Creating publication-ready visualizations (UMAP, violin plots, heatmaps)
- Conducting trajectory inference (pseudotime analysis)
- Comparing cell populations between conditions
πŸ’‘ Examples

Generate Seurat Template

python scripts/main.py --tool seurat --output seurat_analysis.R --species human

Generate Scanpy Template

python scripts/main.py --tool scanpy --output scanpy_analysis.py --species mouse

Generate Both Templates

python scripts/main.py --tool both --output scrna_pipeline --species human --batch-correction harmony --trajectory true

Command-Line Parameters

| Parameter | Type | Required | Description | |-----------|------|----------|-------------| | --tool | string | Yes | Analysis tool: seurat, scanpy, or both | | --output | string | Yes | Output file or directory path | | --species | string | No | Species: human or mouse (default: human) | | --batch-correction | string | No | Method: harmony, rpca, cca, scanorama, scvi | | --trajectory | bool | No | Include trajectory analysis (default: false) | | --cell-communication | bool | No | Include cell-cell communication (default: false) | | --de-analysis | bool | No | Include differential expression (default: false) | | --spatial | bool | No | Include spatial transcriptomics (default: false) |

βš™οΈ Configuration

# Python dependencies
pip install -r requirements.txt

View on ClawHub
TERMINAL
clawhub install single-cell-rnaseq-pipeline

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